Frankly, not much. All three designations come from the same species of plant, so scientifically speaking, there’s no difference whatsoever. Phenotypically speaking, Indica varietals are short and squat plants with dark-green fan leaves, Sativa varietals are taller and skinnier with bright green fan leaves, and hybrid cultivars land somewhere in the middle. Colloquially speaking, Indica strains are thought to be relaxing, Sativa strains are thought to be energetic when you smoke them, and hybrid strains may give you the best of both worlds. 

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